South African study of blast phase chronic myeloid leukaemia: A poor prognostic outlook

• Główni autorzy: Katherine E. Hodkinson (Autor), Nikki Bouwer (Autor), Jenifer Vaughan (Autor)
• Format: Książka
• Wydane: AOSIS, 2022-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background: Chronic myeloid leukaemia (CML) is a haematological malignancy characterised by the translocation t(9;22)(q34;q11.2), resulting in a constitutively active tyrosine kinase. Globally, overall survival of blast crisis phase (BC) CML is one year. Newer tyrosine kinase inhibitors and allogene...