Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy

• Ngā kaituhi matua: Xiao-Li Chen (Author), Yu-Jing Bai (Author), Qin-Rui Hu (Author), Shan-Shan Li (Author), Lv-Zhen Huang (Author), Xiao-Xin Li (Author)
• Hōputu: Pukapuka
• I whakaputaina: Hindawi Limited, 2016-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Background. Epithelial-mesenchymal transition (EMT) of retinal pigment epithelium (RPE) is vital in proliferative vitreoretinopathy (PVR) development. Apoptosis-stimulating proteins of p53 (ASPP2) have recently been reported to participate in EMT. However, the role of ASPP2 in PVR pathogenesis has n...