Albumin-Mediated Size Exclusion Chromatography: The Apparent Molecular Weight of PSMA Radioligands as Novel Parameter to Estimate Their Blood Clearance Kinetics
A meticulously adjusted pharmacokinetic profile and especially fine-tuned blood clearance kinetics are key characteristics of therapeutic radiopharmaceuticals. We, therefore, aimed to develop a method that allowed the estimation of blood clearance kinetics in vitro. For this purpose, <sup>177&...
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Main Authors: | Jan-Philip Kunert (Author), Sebastian Fischer (Author), Alexander Wurzer (Author), Hans-Jürgen Wester (Author) |
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Format: | Book |
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MDPI AG,
2022-09-01T00:00:00Z.
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