Biosynthetic Potential of <i>Streptomyces</i> Rationalizes Genome-Based Bioprospecting
<i>Streptomyces</i> are the most prolific source of structurally diverse microbial natural products. Advancing genome-based analysis reveals the previously unseen potential of <i>Streptomyces</i> to produce numerous novel secondary metabolites, which allows us to take natural...
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| Main Authors: | , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | <i>Streptomyces</i> are the most prolific source of structurally diverse microbial natural products. Advancing genome-based analysis reveals the previously unseen potential of <i>Streptomyces</i> to produce numerous novel secondary metabolites, which allows us to take natural product discovery to the next phase. However, at present there is a huge disproportion between the rate of genome reports and discovery of new compounds. From this perspective of harnessing the enduring importance of <i>Streptomyces</i>, we discuss the recent genome-directed advancements inspired by hidden biosynthetic wealth that provide hope for future antibiotics. |
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| Item Description: | 10.3390/antibiotics10070873 2079-6382 |