Biphasic synovial sarcomas of the liver: a case report and literature review

Abstract Background Synovial sarcoma is a soft tissue sarcoma of temporarily unknown histologic origin with the ability for biphasic differentiation, occurring mostly in the vicinity of large joints of the extremities. Synovial sarcoma that originates in the liver is extremely rare. Only 7 cases hav...

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Main Authors: Defeng Liang (Author), Lingyu Meng (Author), Shanshan Wang (Author), Dan Yi (Author), Yahui Liu (Author)
Format: Book
Published: BMC, 2022-06-01T00:00:00Z.
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LEADER 00000 am a22000003u 4500
001 doaj_24a7a848a01d4e63ae8aca433091f43d
042 |a dc 
100 1 0 |a Defeng Liang  |e author 
700 1 0 |a Lingyu Meng  |e author 
700 1 0 |a Shanshan Wang  |e author 
700 1 0 |a Dan Yi  |e author 
700 1 0 |a Yahui Liu  |e author 
245 0 0 |a Biphasic synovial sarcomas of the liver: a case report and literature review 
260 |b BMC,   |c 2022-06-01T00:00:00Z. 
500 |a 10.1186/s13000-022-01233-4 
500 |a 1746-1596 
520 |a Abstract Background Synovial sarcoma is a soft tissue sarcoma of temporarily unknown histologic origin with the ability for biphasic differentiation, occurring mostly in the vicinity of large joints of the extremities. Synovial sarcoma that originates in the liver is extremely rare. Only 7 cases have been reported in the domestic and international literature. Case presentation We report an 11-year-old female patient who underwent partial hepatectomy for a liver mass. Microscopically, she was diagnosed with hepatic biphasic synovial sarcoma. Cytogenetic examination revealed the fusion gene SS18-SSX1 (+), which confirmed the diagnosis. Conclusion Synovial sarcoma of the liver is a rare malignancy that is difficult to diagnose. Confirmation of diagnosis is based on histopathological assessment combined with immunohistochemical staining and, if necessary, cytogenetic aids. 
546 |a EN 
690 |a Synovial sarcoma 
690 |a Liver 
690 |a Diagnosis 
690 |a Case report 
690 |a Pathology 
690 |a RB1-214 
655 7 |a article  |2 local 
786 0 |n Diagnostic Pathology, Vol 17, Iss 1, Pp 1-5 (2022) 
787 0 |n https://doi.org/10.1186/s13000-022-01233-4 
787 0 |n https://doaj.org/toc/1746-1596 
856 4 1 |u https://doaj.org/article/24a7a848a01d4e63ae8aca433091f43d  |z Connect to this object online.