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A non-synonymous coding change in the <it>CYP19A1 </it>gene Arg264Cys (rs700519) does not affect circulating estradiol, bone structure or fracture

<p>Abstract</p> <p>Background</p> <p>The biosynthesis of estrogens from androgens is catalyzed by aromatase P450 enzyme, coded by the <it>CYP19A1 </it>gene on chromosome 15q21.2. Genetic variation within the <it>CYP19A1 </it>gene sequence has bee...

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Main Authors: Wang Jenny Z (Author), Deogan Mandeep S (Author), Lewis Joshua R (Author), Chew Shelby (Author), Mullin Ben H (Author), McNab Tegan J (Author), Wilson Scott G (Author), Ingley Evan (Author), Prince Richard L (Author)
Format: Book
Published: BMC, 2011-12-01T00:00:00Z.
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