Effect of policosanol from insect wax on amyloid β-peptide-induced toxicity in a transgenic Caenorhabditis elegans model of Alzheimer's disease

• Main Authors: Xin Zhang (Author), Chenjing Ma (Author), Long Sun (Author), Zhao He (Author), Ying Feng (Author), Xian Li (Author), Jin Gan (Author), Xiaoming Chen (Author)
• Format: Book
• Published: BMC, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Alzheimer's disease (AD), an age-related neurodegenerative disorder and a serious public health concern, is mainly caused by β-amyloid (Aβ)-induced toxicity. Currently, a limited number of drugs are effective against AD, and only a few are used for its treatment. According t...