In Silico Design, Synthesis, and Biological Evaluation of Anticancer Arylsulfonamide Endowed with Anti-Telomerase Activity
Telomerase, a reverse transcriptase enzyme involved in DNA synthesis, has a tangible role in tumor progression. Several studies have evidenced telomerase as a promising target for developing cancer therapeutics. The main reason is due to the overexpression of telomerase in cancer cells (85-90%) comp...
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Main Authors: | Giulia Culletta (Author), Mario Allegra (Author), Anna Maria Almerico (Author), Ignazio Restivo (Author), Marco Tutone (Author) |
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Format: | Book |
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MDPI AG,
2022-01-01T00:00:00Z.
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