Prevalence of malaria relapse: systematic review with meta-analysis

• Main Authors: Talita Lima do Nascimento (Author), Suleima Pedroza Vasconcelos (Author), Yara Peres (Author), Mirla Jéssica Sampaio de Oliveira (Author), Monica Taminato (Author), Káren Mendes Jorge de Souza (Author)
• Format: Book
• Published: Universidade de São Paulo, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1518-8345; 10.1590/1518-8345.2619.3111
• Keywords: Malaria; Recurrencia; Prevelencia; Enfermedades Desatendidas; Enfermería en Salud Pública; Nursing; RT1-120
• Source: Revista Latino-Americana de Enfermagem, Vol 27, Iss 0 (2019)

ABSTRACT Objective: systematic review with a meta-analysis of the prevalence of malaria relapse. Method: it consisted in a search for cross-sectional studies, carried out in three databases, without application of filters. A total of 1,924 articles were identified, selected based on eligibility criteria. The selection was made in pairs from the reading of the titles, abstracts and text. The meta-analysis was performed with a statistical program. Results: a sample of 1,308 patients with malaria, ranging from 70 to 586 patients in the study. Relapse was estimated at 0.47%, with a 95% confidence interval and 99.04% of squared i. In the included studies, the prevalence of relapse ranged from 17.00% to 92.85%. The result of the meta-analysis is considered relevant, despite the heterogeneity. Conclusion: relapse is a phenomenon that can contribute to the maintenance of the endemicity of malaria in the world and to introduce it in non-affected areas. In addition, there is the need for advancement in the production of knowledge regarding this disease, to qualify the research methods on prevalence.