Prevalence and risk factors associated with wheezing in the first year of life

OBJECTIVE: to investigate the prevalence and risk factors associated with wheezing in infants in the first year of life. METHODS: this was a cross-sectional study, in which a validated questionnaire (Estudio Internacional de Sibilancias en Lactantes - International Study of Wheezing in Infants - EIS...

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Main Authors: Olivia A. A. Costa Bessa (Author), Álvaro J. Madeiro Leite (Author), Dirceu Solé (Author), Javier Mallol (Author)
Format: Book
Published: Elsevier, 2014-04-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Olivia A. A. Costa Bessa  |e author 
700 1 0 |a Álvaro J. Madeiro Leite  |e author 
700 1 0 |a Dirceu Solé  |e author 
700 1 0 |a Javier Mallol  |e author 
245 0 0 |a Prevalence and risk factors associated with wheezing in the first year of life 
260 |b Elsevier,   |c 2014-04-01T00:00:00Z. 
500 |a 1678-4782 
500 |a 10.1016/j.jped.2013.08.007 
520 |a OBJECTIVE: to investigate the prevalence and risk factors associated with wheezing in infants in the first year of life. METHODS: this was a cross-sectional study, in which a validated questionnaire (Estudio Internacional de Sibilancias en Lactantes - International Study of Wheezing in Infants - EISL) was applied to parents of infants aged between 12 and 15 months treated in 26 of 85 primary health care units in the period between 2006 and 2007. The dependent variable, wheezing, was defined using the following standards: occasional (up to two episodes of wheezing) and recurrent (three or more episodes of wheezing). The independent variables were shown using frequency distribution to compare the groups. Measures of association were based on odds ratio (OR) with a confidence interval of 95% (95% CI), using bivariate analysis, followed by multivariate analysis (adjusted OR [aOR]). RESULTS: a total of 1,029 (37.7%) infants had wheezing episodes in the first 12 months of life; of these, 16.2% had recurrent wheezing. Risk factors for wheezing were family history of asthma (OR = 2.12; 95% CI: 1.76-2.54) and six or more episodes of colds (OR = 2.38; 95% CI: 1.91-2.97) and pneumonia (OR = 3.02; 95% CI: 2.43-3.76). For recurrent wheezing, risk factors were: familial asthma (aOR = 1.73; 95% CI: 1.22-2.46); early onset wheezing (aOR = 1.83; 95% CI: 1.75-3.75); nocturnal symptoms (aOR = 2.56; 95% CI: 1.75-3.75), and more than six colds (aOR = 2.07; 95% CI 1.43- .00). CONCLUSION: the main risk factors associated with wheezing in Fortaleza were respiratory infections and family history of asthma. Knowing the risk factors for this disease should be a priority for public health, in order to develop control and treatment strategies. 
546 |a EN 
690 |a Prevalência 
690 |a Fatores de risco 
690 |a Estudos transversais 
690 |a Lactente 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Jornal de Pediatria, Vol 90, Iss 2, Pp 190-196 (2014) 
787 0 |n http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572014000200190&lng=en&tlng=en 
787 0 |n https://doaj.org/toc/1678-4782 
856 4 1 |u https://doaj.org/article/24f70eae5c2e42c0a8a98dde4d73c294  |z Connect to this object online.