Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

• Main Authors: Thomas W. Winkler (Author), Felix Grassmann (Author), Caroline Brandl (Author), Christina Kiel (Author), Felix Günther (Author), Tobias Strunz (Author), Lorraine Weidner (Author), Martina E. Zimmermann (Author), Christina A. Korb (Author), Alicia Poplawski (Author), Alexander K. Schuster (Author), Martina Müller-Nurasyid (Author), Annette Peters (Author), Franziska G. Rauscher (Author), Tobias Elze (Author), Katrin Horn (Author), Markus Scholz (Author), Marisa Cañadas-Garre (Author), Amy Jayne McKnight (Author), Nicola Quinn (Author), Ruth E. Hogg (Author), Helmut Küchenhoff (Author), Iris M. Heid (Author), Klaus J. Stark (Author), Bernhard H. F. Weber (Author)
• Format: Book
• Published: BMC, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Advanced age-related macular degeneration (AMD) is a leading cause of blindness. While around half of the genetic contribution to advanced AMD has been uncovered, little is known about the genetic architecture of early AMD. Methods To identify genetic factors for early AMD, we co...