Real-world efficacy and safety of pyrotinib in patients with HER2-positive metastatic breast cancer: A prospective real-world study

• Main Authors: Qiongwen Zhang (Author), Ping He (Author), Tinglun Tian (Author), Xi Yan (Author), Juan Huang (Author), Zhang Zhang (Author), Hong Zheng (Author), Xiaorong Zhong (Author), Ting Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Pyrotinib, a novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor, shows encouraging anticancer activity and acceptable tolerability in multiple phase II and phase III randomized clinical trials, but the real-world data of pyrotinib, especially the outcomes in HER2-positive metast...