Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis

Background: The diagnosis of osteomyelitis is invasive and expensive as the current standard technique is the bone biopsy. Our aim was to compare the degree of agreement and concordance between standard bone biopsy and other non-bone techniques. Methods: We performed an electronic search through 12...

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Main Authors: Gehad Mohamed Tawfik (Author), Mahmoud Dibas (Author), Nguyen Minh Dung (Author), Ahmad Awad Alkhebairy (Author), Mona Hanafy Mahmoud (Author), Mohamed Hosny Ibrahim (Author), Nada Ramadan Abd Elhady (Author), Ahmed M. Sayed (Author), Ahmed Samir Gehad (Author), Ahmed Saber Abdelrahman (Author), Muhammed Khaled Elfaituri (Author), Nguyen Hai Nam (Author), Amr Ehab El-Qushayri (Author), Nguyen Tien Huy (Author)
Format: Book
Published: Elsevier, 2020-11-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Gehad Mohamed Tawfik  |e author 
700 1 0 |a Mahmoud Dibas  |e author 
700 1 0 |a Nguyen Minh Dung  |e author 
700 1 0 |a Ahmad Awad Alkhebairy  |e author 
700 1 0 |a Mona Hanafy Mahmoud  |e author 
700 1 0 |a Mohamed Hosny Ibrahim  |e author 
700 1 0 |a Nada Ramadan Abd Elhady  |e author 
700 1 0 |a Ahmed M. Sayed  |e author 
700 1 0 |a Ahmed Samir Gehad  |e author 
700 1 0 |a Ahmed Saber Abdelrahman  |e author 
700 1 0 |a Muhammed Khaled Elfaituri  |e author 
700 1 0 |a Nguyen Hai Nam  |e author 
700 1 0 |a Amr Ehab El-Qushayri  |e author 
700 1 0 |a Nguyen Tien Huy  |e author 
245 0 0 |a Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis 
260 |b Elsevier,   |c 2020-11-01T00:00:00Z. 
500 |a 1876-0341 
500 |a 10.1016/j.jiph.2020.08.010 
520 |a Background: The diagnosis of osteomyelitis is invasive and expensive as the current standard technique is the bone biopsy. Our aim was to compare the degree of agreement and concordance between standard bone biopsy and other non-bone techniques. Methods: We performed an electronic search through 12 electronic databases to retrieve relevant studeis. Our criteria included any original article that reported the degree of agreement and/or the concordance between bone biopsy and other non-bone techniques in diagnosing osteomyelitis. We published our protocol in PROSPERO with a registration number, CRD42017080336. Results: There were 29 studies included in the qualitative analysis, of which 15 studies were included in the meta-analysis. Samples from sinus tract had the highest concordance with bone biopsy samples, while swab samples were the least concordant with bone biopsy samples. Additionally, Staphylococcus aureus was the most common bacteria isolated and the most concordant from samples, compared to other types of causative agents. Sinus tract had a significantly very high degree of agreement with bone samples. S. aureus had the highest degree of agreement in bone smaples. Conclusion: Diagnosis of osteomyelitis using sinus tract swab is close in results' accuracy to bone biopsy. S. aureus was the most common extracted organism found in these samples and had the highest degree of agreement. 
546 |a EN 
690 |a Osteomyelitis 
690 |a Diagnosis 
690 |a Bone biopsy 
690 |a Swab 
690 |a Concordance 
690 |a Infectious and parasitic diseases 
690 |a RC109-216 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n Journal of Infection and Public Health, Vol 13, Iss 11, Pp 1682-1693 (2020) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S1876034120306316 
787 0 |n https://doaj.org/toc/1876-0341 
856 4 1 |u https://doaj.org/article/2562c8223dcf46e48a44f4460d0b9a1d  |z Connect to this object online.