Design, synthesis, molecular docking and anticonvulsant evaluation of novel 6-iodo-2-phenyl-3-substituted-quinazolin-4(3H)-ones

• Asıl Yazarlar: Mohamed-Kamal Ibrahim (Yazar), Khaled El-Adl (Yazar), Ahmed A. Al-Karmalawy (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Faculty of Pharmacy, Cairo University, 2015-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A new series of 6-iodo-2-phenyl-3-substituted-quinazolin-4(3H)-one (5-12a-b) derivatives were synthesized, evaluated for their anticonvulsant activity against pentylenetetrazole (PTZ)-induced seizures and maximal electroshock test and compared with the reference drugs phenobarbital sodium and methaq...