Effect of acute immobilization on the hematological, red-ox and rheological parameters of erythrocytes in rats

Objectives: Immobilization effects on antioxidant enzymes activities, red-ox variables and rheological parameters of erythrocytes were studied. Background: It is not clear to which extent immobilization-induced oxidative stress may affect erythrocyte rheology. Method: Hematological and red-ox variab...

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Main Authors: Artemy V. Novozhilov (Author), Tat'yana V. Tavrovskaya (Author), Michael I. Kalinski (Author), Lev N. Katyukhin (Author), Vadim A. Ivanov (Author), Vladimir I. Morozov (Author)
Format: Book
Published: Al Ameen Medical College, 2013-01-01T00:00:00Z.
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Summary:Objectives: Immobilization effects on antioxidant enzymes activities, red-ox variables and rheological parameters of erythrocytes were studied. Background: It is not clear to which extent immobilization-induced oxidative stress may affect erythrocyte rheology. Method: Hematological and red-ox variables, erythrocyte antioxidant enzymes activities, and rheologic parameters of erythrocytes were analyzed. Result: Immobilization stimulated release of stored erythrocytes and reticulocytes, and decrease in rheology parameters of erythrocytes. There were no significant effects of the immobilization on antioxidant enzymes activities and red-ox variables. Conclusion: Immobilization-induced appearance of stored erythrocytes and reticulocytes in circulation is likely to have contributed to the alterations of erythrocyte rheology than red-ox state of blood.
Item Description:0974-1143