The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects
Background: Vitamin D is one of the known lipoprotein hormones with metabolic properties. We aimed to determine the serum 25-hydroxy vitamin D concentration in overweight/obese subjects with diabetes mellitus type Ⅱ (DM Ⅱ) in association with systolic and diastolic blood pressure and quality of life...
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Babol University of Medical Sciences,
2020-05-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_25a7c3f4e6a34e5082dd33d3f6bcebc4 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Naser Aghamohammadzadeh |e author |
| 700 | 1 | 0 | |a Neda Dolatkhah |e author |
| 700 | 1 | 0 | |a Maryam Hashemian |e author |
| 700 | 1 | 0 | |a Seyed Kazem Shakouri |e author |
| 700 | 1 | 0 | |a Saeed Hasanpour |e author |
| 245 | 0 | 0 | |a The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects |
| 260 | |b Babol University of Medical Sciences, |c 2020-05-01T00:00:00Z. | ||
| 500 | |a 2008-6164 | ||
| 500 | |a 2008-6172 | ||
| 520 | |a Background: Vitamin D is one of the known lipoprotein hormones with metabolic properties. We aimed to determine the serum 25-hydroxy vitamin D concentration in overweight/obese subjects with diabetes mellitus type Ⅱ (DM Ⅱ) in association with systolic and diastolic blood pressure and quality of life compared with healthy participants. Methods: The current case-control study was carried out among 80 overweight/obese subjects with DM Ⅱ, and 77 healthy subjects matched by sex, age and body mass index (BMI). Serum 25-hydroxyvitamin D concentration was measured by ELISA method. In order to examine the quality of life, the Persian version of SF36 questionnaire was used. Results: There was significant difference between diabetic and healthy subjects considering serum 25-hydroxyvitamin D concentration (p=0.012). Serum 25- hydroxyvitamin D concentration was inversely correlated with diastolic blood pressure (p=0.02) and positively associated with physical function (p<0.001), social function (p<0.001) and general health (p<0.001) components of quality of life in diabetic subjects and physical health sub-scale (p=0.004) in all participants. Conclusion: Serum 25-hydroxyvitamin D concentration was significantly lower in diabetic subjects in comparison with healthy controls. There was a significant reverse relationship between serum concentrations of 25-hydroxyvitamin D with diastolic blood pressure and on the other hand, a significant positive relationship with physical function, social function and general health components and physical health subscale of quality of life in participants with DM Ⅱ | ||
| 546 | |a EN | ||
| 690 | |a 25-hydroxy vitamin d | ||
| 690 | |a diabetes mellitus | ||
| 690 | |a blood pressure | ||
| 690 | |a quality of life | ||
| 690 | |a Internal medicine | ||
| 690 | |a RC31-1245 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Caspian Journal of Internal Medicine, Vol 11, Iss 3, Pp 267-277 (2020) | |
| 787 | 0 | |n http://caspjim.com/article-1-1914-en.html | |
| 787 | 0 | |n https://doaj.org/toc/2008-6164 | |
| 787 | 0 | |n https://doaj.org/toc/2008-6172 | |
| 856 | 4 | 1 | |u https://doaj.org/article/25a7c3f4e6a34e5082dd33d3f6bcebc4 |z Connect to this object online. |