Sulfasalazine Microparticles Targeting Macrophages for the Treatment of Inflammatory Diseases Affecting the Synovial Cavity

• Main Authors: Monica-Carolina (Author), Ana Fernández-Carballido (Author), Carolina Hurtado (Author), Emilia Barcia (Author), Consuelo Montejo (Author), Mario Alonso (Author), Sofia Negro (Author)
• Format: Bog
• Udgivet: MDPI AG, 2021-06-01T00:00:00Z.
• Fag: article
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Rheumatoid arthritis (RA) is a chronic inflammatory disease with sulfasalazine (SSZ) extensively used for long-term treatment of both juvenile and adult RA. Its use is associated with adverse effects and toxicity due to its non-selective biodistribution. Macrophages play an important role in inflamm...