Sulfasalazine Microparticles Targeting Macrophages for the Treatment of Inflammatory Diseases Affecting the Synovial Cavity

• Autores principales: Monica-Carolina (Autor), Ana Fernández-Carballido (Autor), Carolina Hurtado (Autor), Emilia Barcia (Autor), Consuelo Montejo (Autor), Mario Alonso (Autor), Sofia Negro (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2021-06-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Rheumatoid arthritis (RA) is a chronic inflammatory disease with sulfasalazine (SSZ) extensively used for long-term treatment of both juvenile and adult RA. Its use is associated with adverse effects and toxicity due to its non-selective biodistribution. Macrophages play an important role in inflamm...