Sulfasalazine Microparticles Targeting Macrophages for the Treatment of Inflammatory Diseases Affecting the Synovial Cavity

• Egile Nagusiak: Monica-Carolina (Egilea), Ana Fernández-Carballido (Egilea), Carolina Hurtado (Egilea), Emilia Barcia (Egilea), Consuelo Montejo (Egilea), Mario Alonso (Egilea), Sofia Negro (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Rheumatoid arthritis (RA) is a chronic inflammatory disease with sulfasalazine (SSZ) extensively used for long-term treatment of both juvenile and adult RA. Its use is associated with adverse effects and toxicity due to its non-selective biodistribution. Macrophages play an important role in inflamm...