Sulfasalazine Microparticles Targeting Macrophages for the Treatment of Inflammatory Diseases Affecting the Synovial Cavity

• Main Authors: Monica-Carolina (Author), Ana Fernández-Carballido (Author), Carolina Hurtado (Author), Emilia Barcia (Author), Consuelo Montejo (Author), Mario Alonso (Author), Sofia Negro (Author)
• 格式: 图书
• 出版: MDPI AG, 2021-06-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Rheumatoid arthritis (RA) is a chronic inflammatory disease with sulfasalazine (SSZ) extensively used for long-term treatment of both juvenile and adult RA. Its use is associated with adverse effects and toxicity due to its non-selective biodistribution. Macrophages play an important role in inflamm...