Cover Image

Synthesis, Antibacterial study and ADME Evaluation of Novel Isonicotinoyl Hydrazide Derivative Containing 1,3,4-Oxadiazole Moiety

Novel derivative of isoniazid containing 1,3,4-oxadiazole pharmacophore has been synthesized. The chemical structure of the compound was characterized and confirmed by using FT-IR and 1H-NMR spectroscopy. The desired compound was tested against gram-positive and gram-negative bacteria using agar w...

Full description

Saved in:

Bibliographic Details
Main Authors:	Mazen Mohammed Jwaid (Author), Karima Fadhil Ali (Author), Mayada Hadi Abd-alwahab (Author)
Format:	Book
Published:	College of Pharmacy / Mustansiriyah University, 2022-04-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis and antimicrobial evaluation of Histidine Cinnamaldehyde Schiff base containing structural feature of 1, 3, 4-thiadiazole heterocyclic moiety
by: Doaa Mahmood Ibrahim, et al.
Published: (2020)

Synthesis and antimicrobial evaluation of Histidine Cinnamaldehyde Schiff base containing structural feature of 1, 3, 4-thiadiazole heterocyclic moiety
by: Doaa Mahmood Ibrahim, et al.
Published: (2024)

Synthesis and investigation of antimicrobial activities of nitrofurazone analogues containing hydrazide-hydrazone moiety
by: Łukasz Popiołek, et al.
Published: (2017)

Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitors
by: Xiao-Yan Jin, et al.
Published: (2019)

Synthesis, telomerase inhibitory and anticancer activity of new 2-phenyl-4H-chromone derivatives containing 1,3,4-oxadiazole moiety
by: Xu Han, et al.
Published: (2021)

The Effect of Azo Moiety on the Electrical Conductivity of Oxadiazole and Triazole Containing Polymers
by: Saja Ibrahim, et al.
Published: (2022)

In-silico ADME prediction and molecular docking study of novel benzimidazole-1,3,4-oxadiazole derivatives as CYP51 inhibitors for antimicrobial activity
by: Shivanand Kolageri, et al.
Published: (2022)

Synthesis of Some New Substituted 1,3,4-Oxadiazole and 1,3,4-Thiadiazole Derivatives
by: Amena A. Ahmed
Published: (2018)

Synthesis of Some Substituted 1,3,4-Oxadiazoles from Hydrazones
by: Khalid Daoud, et al.
Published: (2009)

Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives
by: Camelia Elena Stecoza, et al.
Published: (2021)

Synthesis, Characterization and Antibacterial Activity of New Derivatives of Imidazolidine having Sulfamethoxazole Moiety
by: Enas k. Abd alazez, et al.
Published: (2019)

Synthesis, in silico analysis and antidepressant activity of 1,3,4-oxadiazole derivatives
by: Banylla Felicity Dkhar Gatphoh, et al.
Published: (2022)

Synthesis and Characterization of New 1,3,4-Oxadiazole Derivatives from Sulfathiazole
by: Jassim Jassim, et al.
Published: (2024)

Molecular docking, ADMET, synthesis and evaluation of new indomethacin hydrazide derivatives as antibacterial agents
by: Yaseen S. Hamdoon, et al.
Published: (2024)

Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review
by: Jing-Jing Wang, et al.
Published: (2022)

Synthesis, antibacterial and anticancer activity, and docking study of aminoguanidines containing an alkynyl moiety
by: Xianqing Deng, et al.
Published: (2020)

Synthesis of some substituted 1,3,4-oxadiazoles, thiadiazoles and 1,2,4-triazoles
by: Shereen R. Mohamed
Published: (2009)

Synthesis of 1,3,4-Oxadiazole Derivatives from Ethyl-2-Piperidone-3-Carboxylate
by: M. A. Sheat, et al.
Published: (2012)

Synthesis and antimicrobial evaluation of some 2,5 disubstituted 1,3,4-oxadiazole derivatives
by: Elham Jafari, et al.
Published: (2017)

Synthesis, characterization and biological evaluation of novel 2,5 substituted-1,3,4 oxadiazole derivatives
by: Selvaraj Kavitha, et al.
Published: (2017)

Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives
by: Shailesh Pathak, et al.
Published: (2020)

Synthesis, characterization and pharmacological evaluation of different 1,3,4-oxadiazole and acetamide derivatives of ethyl nipecotate
by: Khadija Nafeesa, et al.
Published: (2017)

In silico and antithrombotic studies of 1,3,4-oxadiazoles derived from benzimidazole
by: B. Vishwanathan, et al.
Published: (2015)

Synthesis of some new 5-substituted-2-((6-chloro-3,4-methylenedioxyphenyl)methylthio)-1,3,4-oxadiazole derivatives as suitable antibacterial inhibitors
by: Aziz-, et al.
Published: (2015)

Synthesis, Characterization, ADME Study and Antimicrobial Evaluation of New 1,2,3-triazole Derivatives of 2-phenyl benzimidazole.
by: Asmaa Adnan Abdulnabi, et al.
Published: (2023)

Naproxen Based 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors: Design, Synthesis, Anticancer, and Computational Studies
by: Mohammad Mahboob Alam, et al.
Published: (2021)

Synthesis of Some Heterocyclic Compounds Containing Tetrahydroisoquinoline Moiety
by: Mohammad Al-Iraqi, et al.
Published: (2013)

Synthesis of some novel enzyme inhibitors and antibacterial agents derived from 5-(1-(4-tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol
by: Almas Sattar, et al.

Synthesis of Some Substituted 1,3,4-Oxadiazoles, Thiadiazoles and 1,2,4-Triazoles from Acid Chlorides
by: E. Q. Mahmood, et al.
Published: (2013)

Synthesis of 2-Isobutyl, 2-Isobutyl-5-aryl and 2-Isobutyl-5-thiol-1,3,4-Oxadiazoles
by: Hadil S. Aziz, et al.
Published: (2007)

Synthesis and characterization Studies of Mixed Ligand (1,3,4-oxadiazole derivative and ethylenediamine or acetylacetone)complexes with Ni(II)
by: Rezhna Faraj, et al.
Published: (2013)

Design, synthesis and in vitro antiproliferative activity of new thiazolidinedione-1,3,4-oxadiazole hybrids as thymidylate synthase inhibitors
by: Zohor Mohammad Mahdi Alzhrani, et al.
Published: (2020)

The study of antiexudative action of S-alkylated 1,3,4-oxadiazole-3-thionе derivatives
by: Yu. L. Shepeta, et al.
Published: (2019)

Synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles from 2-(2,3-dimethylphenyl amino) benzoic acid
by: Khalid Daoud, et al.
Published: (2009)

Synthesis, characterization, antimicrobial, and pharmacological evaluation of some 2, 5-disubstituted sulfonyl amino 1,3,4-oxadiazole and 2-amino-disubstituted 1,3,4-thiadiazole derivatives
by: Dilipkumar Pal, et al.
Published: (2014)

Biologically oriented synthesis of medicines (BIODS) based on heterylpoxid 2,5-disubstituted 1,3,4-oxadiazoles (Part 2)
by: Yu. V. Karpenko, et al.
Published: (2021)

Biologically oriented synthesis of medicines (BIODS) based on heterylpoxid 2,5- disubstituted 1,3,4-oxadiazoles (Part 1)
by: Yu. V. Karpenko, et al.
Published: (2020)

Synthesis, Computational Studies, Antioxidant and Anti-Inflammatory Bio-Evaluation of 2,5-Disubstituted-1,3,4-Oxadiazole Derivatives
by: Sibghat Mansoor Rana, et al.
Published: (2023)

In silico Study of New Five-Membered Heterocyclic Derivatives Bearing (1,3,4-oxadiazole and 1,3,4-thiadiazole) As Promising Cyclooxygenase Inhibitors
by: Safa Adnan Mahmood, et al.
Published: (2024)

An Understanding of Mechanism-Based Approaches for 1,3,4-Oxadiazole Scaffolds as Cytotoxic Agents and Enzyme Inhibitors
by: Davinder Kumar, et al.
Published: (2023)