Pancreatic insulinoma causing hypoglycemic episodes

Background: Insulinoma typically has non-specific neuroglycopenic symptoms. It is a neuroendocrine tumor of the pancreas, and leads to recurring hypoglycemic attacks stemming from insulin hypersecretion. Purpose: We report the case of an 8-year-old boy who was diagnosed with insulinoma following ref...

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Bibliographic Details
Main Authors: Moaffaq Mahdi (Author), Bassel Almehman (Author), Safi Nassan (Author), Soliman Binyahib (Author)
Format: Book
Published: Elsevier, 2020-06-01T00:00:00Z.
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Summary:Background: Insulinoma typically has non-specific neuroglycopenic symptoms. It is a neuroendocrine tumor of the pancreas, and leads to recurring hypoglycemic attacks stemming from insulin hypersecretion. Purpose: We report the case of an 8-year-old boy who was diagnosed with insulinoma following referral to our hospital for recurrent hypoglycemic attacks. Results: Abdominal computed tomography scan revealed a lesion at the tail of the pancreas. He tested negative for MEN1 (multiple endocrine neoplasia type 1) syndrome. We performed laparoscopic enucleation of the tumor, and he was discharged home 3 days post-operation with normal blood sugar levels. Five years on, there has been no recurrence of hypoglycemic attacks. Conclusion: Insulinoma is one of the important causes of hypoglycemia in a pediatric age group. Surgery is the mainstay of treatment of insulinoma. Pre-operative localization can be achieved mostly by a single modality, or otherwise multiple modalities in other cases. Minimally invasive enucleation of insulinoma in a pediatric age group is safe and feasible for selective cases, which can preserve normal pancreatic tissue without increasing postoperative complications.
Item Description:2213-5766
10.1016/j.epsc.2020.101466