Levels of 8-OxodG Predict Hepatobiliary Pathology in Opisthorchis viverrini Endemic Settings in Thailand.

• Main Authors: Prasert Saichua (Author), Anna Yakovleva (Author), Christine Kamamia (Author), Amar R Jariwala (Author), Jiraporn Sithithaworn (Author), Banchob Sripa (Author), Paul J Brindley (Author), Thewarach Laha (Author), Eimorn Mairiang (Author), Chawalit Pairojkul (Author), Narong Khuntikeo (Author), Jason Mulvenna (Author), Paiboon Sithithaworn (Author), Jeffrey M Bethony (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Opisthorchis viverrini is distinct among helminth infections as it drives a chronic inflammatory response in the intrahepatic bile duct that progresses from advanced periductal fibrosis (APF) to cholangiocarcinoma (CCA). Extensive research shows that oxidative stress (OS) plays a critical role in th...