Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms

• मुख्य लेखकों: Vincent Kam Wai Wong (लेखक), Wu Zeng (लेखक), Juan Chen (लेखक), Xiao Jun Yao (लेखक), Elaine Lai Han Leung (लेखक), Qian Qian Wang (लेखक), Pauline Chiu (लेखक), Ben C. B. Ko (लेखक), Betty Yuen Kwan Law (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Emerging evidence suggests the therapeutic role of autophagic modulators in cancer therapy. This study aims to identify novel traditional Chinese medicinal herbs as potential anti-tumor agents through autophagic induction, which finally lead to autophagy mediated-cell death in apoptosis-resistant ca...