Metformin therapy in a hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during superovulation

• Hoofdauteurs: Sabatini Mary E (Auteur), Guo Lankai (Auteur), Lynch Maureen P (Auteur), Doyle Joseph O (Auteur), Lee HoJoon (Auteur), Rueda Bo R (Auteur), Styer Aaron K (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2011-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Metformin, an oral biguanide traditionally used for the treatment of type 2 diabetes, is widely used for the management of polycystic ovary syndrome (PCOS)-related anovulation. Because of the significant prevalence of insulin resista...