Population Pharmacokinetic/Pharmacodynamic Analysis of Intravenous Zanamivir in Healthy Adults and Hospitalized Adult and Pediatric Subjects With Influenza

• Main Authors: Peiying Zuo (Author), Jon Collins (Author), Malek Okour (Author), Aline Barth (Author), Denise Shortino (Author), Phillip Yates (Author), Grace Roberts (Author), Helen A. Watson (Author), Amanda Peppercorn (Author), Mohammad Hossain (Author)
• Format: Book
• Published: Wiley, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zanamivir is a potent and highly selective inhibitor of influenza neuraminidase in which the inhibition of this enzyme prevents the virus from infecting other cells and specifically prevents release of the new virion from the host cell membrane. It is available as an oral powder for inhalation and i...