Radiosynthesis and Preclinical Evaluation of Bispecific PSMA/FAP Heterodimers for Tumor Imaging

• Main Authors: Kongzhen Hu (Author), Li Li (Author), Yong Huang (Author), Shimin Ye (Author), Jiawei Zhong (Author), Qingsong Yan (Author), Yuhua Zhong (Author), Lilan Fu (Author), Pengju Feng (Author), Hongsheng Li (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Due to tumor heterogeneity and complex tumor-stromal interactions in multicellular systems, the efficiency of monospecific tracers for tumor diagnosis and therapy is currently limited. In light of the evidence of prostate-specific membrane antigen (PSMA) overexpression in tumor cells and fibroblast...