In Vitro and In Silico Evaluation of Antiproliferative Activity of New Isoxazolidine Derivatives Targeting EGFR: Design, Synthesis, Cell Cycle Analysis, and Apoptotic Inducers

A series of novel enantiopure isoxazolidine derivatives were synthesized and evaluated for their anticancer activities against three human cancer cell lines such as human breast carcinoma (MCF-7), human lung adenocarcinoma (A-549), and human ovarian carcinoma (SKOV3) by employing MTT assay. The synt...

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Main Authors: Fahad Alminderej (Author), Siwar Ghannay (Author), Mohamed O. Elsamani (Author), Fahad Alhawday (Author), Abuzar E. A. E. Albadri (Author), Serag Eldin I. Elbehairi (Author), Mohammad Y. Alfaifi (Author), Adel Kadri (Author), Kaïss Aouadi (Author)
格式: 圖書
出版: MDPI AG, 2023-07-01T00:00:00Z.
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