Formulasi Sediaan Salep Ekstrak Minyak Atsiri Daun Jeruk Purut (Citrus Hystrix DC.) terhadap Jamur Candida Albicans
<p><em>T</em><em>he purpose of this</em><em> study </em><em>was</em><em> to formulate essential oils in ointment preparations with different bases and to determine the physical properties and antifungal activity against Candida albicans.<...
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| Format: | Book |
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Prodi Kesehatan Masyarakat FKM UIN Sumatera Utara Medan,
2022-01-01T00:00:00Z.
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| Summary: | <p><em>T</em><em>he purpose of this</em><em> study </em><em>was</em><em> to formulate essential oils in ointment preparations with different bases and to determine the physical properties and antifungal activity against Candida albicans.</em><em> </em><em>The essential oil of kaffir lime leaves was obtained by distillation using the water distillation method and the raw material of fresh kaffir lime leaves was 1.5 k</em><em>ilograms</em><em> which was then identified with Sudan III reagent and formulated in ointment preparations.</em><em> </em><em>The ointment is made with FI, FII, and FIII base formulations with an active substance concentration of 7%. The FIII ointment base had the best evaluation results and was continued for antifungal testing against Candida albicans.</em><em> </em><em>From the research results obtained % yield of essential oil of kaffir lime leaves is 1.533%. The results of the phytochemical identification test showed positive results with the formation of an even red color in the solution.</em><em> </em><em>The results of the evaluation of the ointment preparations showed that FIII had the best evaluation results and continued antifungal testing with a positive control of 2% miconazole nitrate cream.</em><em> </em><em>The average diameter obtained is 8.43 mm and is included in the medium category.</em><em> </em><em>The results of the Shapiro Wilk normality test showed that the research data was normally distributed and homogeneous, then the One-Way ANOVA test was carried out and a significance value of P<0.05 was obtained, and the LSD test showed a significant difference seen from the significance value obtained P<0.05.</em><em></em></p><p><em> </em></p> |
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| Item Description: | 2548-2173 2580-281X 10.30829/jumantik.v6i4.10270 |