The expression of IGFBP-5 in the reproductive axis and effect on the onset of puberty in female rats

• Main Authors: Zhiqiu Yao (Author), Maosen Lin (Author), Tao Lin (Author), Xinbao Gong (Author), Pin Qin (Author), Hailing Li (Author), Tiezhu Kang (Author), Jing Ye (Author), Yanyun Zhu (Author), Qiwen Hong (Author), Ya Liu (Author), Yunsheng Li (Author), Juhua Wang (Author), Fugui Fang (Author)
• Format: Book
• Published: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Insulin-like growth factor-binding protein-5 (IGFBP-5) has recently been shown to alter the reproductive capacity by regulating insulin-like growth factor (IGF) bioavailability or IGF-independent effects. The present study aimed to investigate the effect and mechanism of IGFBP-5 on the onse...