Cover Image

Effect of Angiotensin-Converting-Enzyme Inhibitor and Angiotensin II Receptor Antagonist Treatment on ACE2 Expression and SARS-CoV-2 Replication in Primary Airway Epithelial Cells

Rationale: SARS-CoV-2 gains entrance to airway epithelial cells (AECs) through binding of the viral spike protein to the angiotensin-converting enzyme 2 (ACE2) on the cell surface. However, ACE2 also converts angiotensin II into angiotensin-(1-7) and counterbalances the renin-angiotensin-aldosterone...

Full description

Saved in:

Bibliographic Details
Main Authors:	Oghenemega Okoloko (Author), Elizabeth R. Vanderwall (Author), Lucille M. Rich (Author), Maria P. White (Author), Stephen R. Reeves (Author), Whitney E. Harrington (Author), Kaitlyn A. Barrow (Author), Jason S. Debley (Author)
Format:	Book
Published:	Frontiers Media S.A., 2021-11-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors
by: Daniel eClayton, et al.
Published: (2015)

Commentary: Effect of Angiotensin-Converting-Enzyme Inhibitor and Angiotensin II Receptor Antagonist Treatment on ACE2 Expression and SARS-CoV-2 Replication in Primary Airway Epithelial Cells
by: Fedor Simko, et al.
Published: (2022)

Association of Angiotensin Converting Enzyme (ACE) Gene Polymorphism and Diabetic Nephropathy
by: T Golmohamadi, et al.
Published: (2006)

Association of Angiotensin Converting Enzyme (ACE) Gene Polymorphism and Diabetic Nephropathy
by: T Golmohamadi, et al.
Published: (2006)

A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) unlinked to the ACE gene
by: Adeyemo Adebowale A, et al.
Published: (2008)

Angiotensin-converting enzyme 2 (ACE2): SARS-CoV-2 receptor and RAS modulator
by: Jingwei Bian, et al.
Published: (2021)

Angiotensin converting enzyme 2 (ACE2) - the major receptor for SARS-CoV-2 virus
by: Sonia Frankowska, et al.
Published: (2021)

Natural Products Modulating Angiotensin Converting Enzyme 2 (ACE2) as Potential COVID-19 Therapies
by: Murtala Bello Abubakar, et al.
Published: (2021)

Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2
by: Carlos P. Vio, et al.
Published: (2020)

The angiotensin-converting enzyme 2 (ACE2) receptor in the prevention and treatment of COVID-19 are distinctly different paradigms
by: Craig Steven McLachlan
Published: (2020)

Variations of the Angiotensin converting enzyme (ACE) gene on the explosion performance of badminton athletes
by: Arimbi Arimbi, et al.
Published: (2022)

Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats
by: Xue Mei, et al.
Published: (2023)

Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Angiotensin-Converting Enzyme 2 Levels: A Comprehensive Analysis Based on Animal Studies
by: Gábor Kriszta, et al.
Published: (2021)

Study of angiotensin converting enzyme (ACE) inhibitory effects of main Papaver spp. alkaloids
by: SA Ziai, et al.
Published: (2004)

Chitotriosidase: Providing confirmation of cutaneous sarcoidosis when angiotensin converting enzyme fails
by: Carlie Reeves, BA, MS, et al.
Published: (2024)

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers in an outbreak of SARS-CoV-2
by: Didar Yanardag Acik
Published: (2020)

Correction: Angiotensin-Converting Enzyme (ACE) 2 Overexpression Ameliorates Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition
by: Chun Xi Liu, et al.
Published: (2022)

In silico design of angiotensin-converting enzyme 2 (ACE2) recombinant protein to block the S1 protein pathway of COVID-19 virus
by: Yaser Ghazi
Published: (2020)

Angiotensin-converting enzyme inhibitors
by: David García Barreto, et al.
Published: (2014)

The Fetal Safety of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers
by: Myla E. Moretti, et al.
Published: (2012)

Tissue Angiotensin II Generating System by Angiotensin-Converting Enzyme and Chymase
by: Mizuo Miyazaki, et al.
Published: (2006)

Five-Membered Nitrogen Heterocycles Angiotensin-Converting Enzyme (ACE) Inhibitors Induced Angioedema: An Underdiagnosed Condition
by: Niki Papapostolou, et al.
Published: (2024)

Local Angiotensin-Converting Enzyme 2 Gene Expression in Kidney Allografts Is Not Affected by Renin-Angiotensin-Aldosterone Inhibitors
by: Monika Cahova, et al.
Published: (2021)

The Impact of Angiotensin-Converting Enzyme-2/Angiotensin 1-7 Axis in Establishing Severe COVID-19 Consequences
by: Minela Aida Maranduca, et al.
Published: (2022)

Angiotensin-Converting Enzyme Inhibitor Does Not Suppress Renal Angiotensin II Levels in Angiotensin I-Infused Rats
by: Keisuke Ohnishi, et al.
Published: (2013)

Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study
by: Teodoro J. Oscanoa, et al.
Published: (2020)

Potential angiotensin converting enzyme (ACE) inhibitors from Iranian traditional plants described by Avicenna's Canon of Medicine
by: zohreh kamrani, et al.
Published: (2019)

Angiotensin converting enzyme (ACE) inhibitors activity from purified compounds Fructus Phaleria macrocarpa (Scheff) Boerl
by: Aprilita Rina Yanti Eff, et al.
Published: (2023)

Naphtoyl-Glycyl-Glycyl-Glycine: A New Substrate for Angiotensin Converting Enzyme (ACE) Assay Using HPLC
by: Mohammad kazem Papan, Niusha Sharifi, Mohsen Zeeb, Seyed Reza Hosseini Sedeh, Massoud Amanlou
Published: (2016)

Angiotensin‐converting enzyme 2 deficiency accelerates and angiotensin 1‐7 restores age‐related muscle weakness in mice
by: Hikari Takeshita, et al.
Published: (2018)

Effects of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Contrast-Induced Nephropathy
by: Letian Zhou, et al.
Published: (2014)

Angiotensin-Converting Enzyme 2 (ACE2) in the Context of Respiratory Diseases and Its Importance in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
by: Enrique Ambrocio-Ortiz, et al.
Published: (2021)

Urinary Angiotensin Converting Enzyme 2 Increases in Patients With Type 2 Diabetic Mellitus
by: Yaoxian Liang, et al.
Published: (2015)

Potential Simultaneous Inhibitors of Angiotensin-Converting Enzyme 2 and Transmembrane Protease, Serine 2
by: Ching-Yuan Wu, et al.
Published: (2020)

Serum angiotensin converting enzyme in pemphigus vulgaris
by: Reza M Robati, et al.
Published: (2014)

Angiotensin-converting enzyme polymorphism and pediatric pneumonia
by: Nihal El Rifai, et al.
Published: (2018)

Anti-Inflammatory Properties of Drugs Used to Control COVID-19 and their Effects on the Renin-Angiotensin System and Angiotensin-Converting Enzyme-2
by: Hamed Gilzad-Kohan, et al.
Published: (2020)

Reimbursement policy optimization for Angiotensin-converting enzyme (ACE) inhibitors in Bulgaria: Controlling expenditure without undermining access to treatment
by: Rossen M Kazakov, et al.
Published: (2015)

COVID-19 and aerobic exercise: possible role of angiotensin converting enzyme 2
by: Haidar Djemai, et al.
Published: (2022)

Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats
by: Alexis A. Gonzalez, et al.
Published: (2019)