Revisiting the Checkerboard to Inform Development of β-Lactam/β-Lactamase Inhibitor Combinations
A two-dimensional "checkerboard" array employing systematic titration (e.g., serial two-fold dilutions) is a well-established in vitro method for exploring the antibacterial effects of novel drug combinations. Minimum inhibitory concentrations (MICs) on the checkerboard are isoeffective po...
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MDPI AG,
2024-04-01T00:00:00Z.
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