Preventing Aggregation of Recombinant Interferon beta-1b in Solution by Additives: Approach to an Albumin-Free Formulation
Purpose: Aggregation suppressing additives have been used to stabilize proteins during manufacturing and storage. Interferonβ-1b is prone to aggregation because of being non-glycosylated. Aggregation behavior of albumin-free formulations of recombinant IFNβ-1b was explored using additives such as n-...
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Main Authors: | Najmeh Mahjoubi (Author), Mohammad Reza Fazeli (Author), Rassoul Dinarvand (Author), Mohammad Reza Khoshayand (Author), Ahmad Fazeli (Author), Mohammad Taghavian (Author), Hossein Rastegar (Author) |
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Format: | Book |
Published: |
Tabriz University of Medical Sciences,
2015-11-01T00:00:00Z.
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