CLINICAL AND LABORATORY CHARACTERISTICS OF THE INFECTION CAUSED BY ENTEROVIRUS-71

Adverse course of enterovirus-71 infection (EVI-71) in children, frequent development of the nervous system pathology determine the need for early disease diagnosis. The study included 139 children aged 6 months to 13 years. Modern EVI-71 features is a frequent defeat of children aged from 3 to 7 ye...

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Bibliographic Details
Main Authors: E. N. Simovanyan (Author), V. B. Denisenko (Author), L. F. Bovtalo (Author), L. V. Belugina (Author), M. A. Kim (Author), Yu. S. Kuhol (Author)
Format: Book
Published: LLC "Diagnostics and Vaccines", 2015-08-01T00:00:00Z.
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Summary:Adverse course of enterovirus-71 infection (EVI-71) in children, frequent development of the nervous system pathology determine the need for early disease diagnosis. The study included 139 children aged 6 months to 13 years. Modern EVI-71 features is a frequent defeat of children aged from 3 to 7 years, attending organized groups, the priority development of combined moderate severity forms without nervous system pathology. EVI-71 is characterized by cyclical course, appearance in the first two disease days fever, murrain-like, catarrhal, lymphoproliferative syndromes, conjunctivitis, headaches. The second stage of the disease (3- 6 days) in 37.9% children accompanied by attaching of meningitis and meningoencephalitis symptoms (common cerebral, meningeal and encephalic syndromes, changes in cerebrospinal fluid). In the EVI-71 diagnosis must be observed epidemiological history, clinical and laboratory parameters, detection of enterovirus-71 and its RNA from feces, oropharyngeal mucus and cerebrospinal fluid. Patients with EVI-71 need for combined treatment, including causal agents and pathogenetic therapy.
Item Description:2072-8107
10.22627/2072-8107-2014-13-3-12-19