Improved Computational Identification of Drug Response Using Optical Measurements of Human Stem Cell Derived Cardiomyocytes in Microphysiological Systems

• Главные авторы: Karoline Horgmo Jæger (Автор), Verena Charwat (Автор), Bérénice Charrez (Автор), Henrik Finsberg (Автор), Mary M. Maleckar (Автор), Samuel Wall (Автор), Kevin E. Healy (Автор), Aslak Tveito (Автор)
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• Опубликовано: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Предметы: article
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Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) hold great potential for drug screening applications. However, their usefulness is limited by the relative immaturity of the cells' electrophysiological properties as compared to native cardiomyocytes in the adult huma...