Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding

• Principais autores: Lin Zhu (Autor), Jeanne Shi (Autor), Thao N. Luu (Autor), Joshua C. Neuman (Autor), Elijah Trefts (Autor), Sophia Yu (Autor), Brian T. Palmisano (Autor), David H. Wasserman (Autor), MacRae F. Linton (Autor), John M. Stafford (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2018-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objective: Hepatocyte deletion of estrogen receptor alpha (LKO-ERα) worsens fatty liver, dyslipidemia, and insulin resistance in high-fat diet fed female mice. However, whether or not hepatocyte ERα regulates reverse cholesterol transport (RCT) in mice has not yet been reported. Methods and results:...