Mapping of proteomic lysate of a MCF-7 cancer cell line for the identification of potential markers for breast cancer
Mass spectrometric mapping of proteomic lysate of a MCF-7 cancer cell line was carried out, which identified 153 proteins having molecular weights of 5000 to 630000 Da, a high proportion of which was cytoplasmic and nuclear proteins. The latter accounted for 60 % of their total number whereas the pr...
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2014-07-01T00:00:00Z.
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| 001 | doaj_2843f70f632b4c52b0ac271e7ea0f673 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a V. E. Shevchenko |e author |
| 700 | 1 | 0 | |a M. A. Taipov |e author |
| 700 | 1 | 0 | |a S. V. Kovalev |e author |
| 700 | 1 | 0 | |a N. E. Arnotskaya |e author |
| 700 | 1 | 0 | |a O. M. Pavlova |e author |
| 700 | 1 | 0 | |a I. A. Kudryavtsev |e author |
| 700 | 1 | 0 | |a Z. N. Nikiforova |e author |
| 245 | 0 | 0 | |a Mapping of proteomic lysate of a MCF-7 cancer cell line for the identification of potential markers for breast cancer |
| 260 | |b ABV-press, |c 2014-07-01T00:00:00Z. | ||
| 500 | |a 1994-4098 | ||
| 500 | |a 1999-8627 | ||
| 500 | |a 10.17650/1994-4098-2012-0-2-4-10 | ||
| 520 | |a Mass spectrometric mapping of proteomic lysate of a MCF-7 cancer cell line was carried out, which identified 153 proteins having molecular weights of 5000 to 630000 Da, a high proportion of which was cytoplasmic and nuclear proteins. The latter accounted for 60 % of their total number whereas the proportion of extracellular and membrane proteins constituted 13 %. After using some selection criteria to analyze the findings, the authors present a list of 31 potential biomarkers and describe 12 promising breast anticancer therapeutic targets. | ||
| 546 | |a RU | ||
| 690 | |a breast cancer | ||
| 690 | |a mcf-7 cancer cell line | ||
| 690 | |a proteomics | ||
| 690 | |a mass spectrometry | ||
| 690 | |a biomarkers | ||
| 690 | |a therapeutic targets | ||
| 690 | |a Gynecology and obstetrics | ||
| 690 | |a RG1-991 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Опухоли женской репродуктивной системы, Vol 0, Iss 2, Pp 4-10 (2014) | |
| 787 | 0 | |n https://ojrs.abvpress.ru/ojrs/article/view/91 | |
| 787 | 0 | |n https://doaj.org/toc/1994-4098 | |
| 787 | 0 | |n https://doaj.org/toc/1999-8627 | |
| 856 | 4 | 1 | |u https://doaj.org/article/2843f70f632b4c52b0ac271e7ea0f673 |z Connect to this object online. |