Development of hepatocellular adenomas and carcinomas in mice with liver-specific G6Pase-α deficiency
Glycogen storage disease type 1a (GSD-1a) is caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α), and is characterized by impaired glucose homeostasis and a high risk of developing hepatocellular adenomas (HCAs). A globally G6Pase-α-deficient (G6pc−/−) mouse model that shows pathological fe...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Book |
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The Company of Biologists,
2014-09-01T00:00:00Z.
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