Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition
Here we report the application of a multi-disciplinary protocol for investigating thiazolidin-4-one-based compounds as new promising anti-inflammatory agents interfering with the eicosanoid biosynthesis pathways. The workflow foresaw the generation of a focused virtual library of ∼4.2 × 104 molecu...
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Main Authors: | Ester Colarusso (Author), Marianna Potenza (Author), Gianluigi Lauro (Author), Maria Giovanna Chini (Author), Valentina Sepe (Author), Angela Zampella (Author), Katrin Fischer (Author), Robert K. Hofstetter (Author), Oliver Werz (Author), Giuseppe Bifulco (Author) |
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Format: | Book |
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Elsevier,
2022-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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