MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma

MicroRNAs (miRNAs) can regulate tumor cell invasion and metastasis in a tumor-specific manner. We recently demonstrated that global downregulation of miRNAs after deleting dicer can promote development of distant metastases in a mouse model of primary soft tissue sarcoma (STS). In this study, we ide...

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Bibliographic Details
Main Authors: Mohit Sachdeva (Author), Melody J. Whitley (Author), Jeffrey K. Mito (Author), Yan Ma (Author), Dina C. Lev (Author), Diana M. Cardona (Author), David G. Kirsch (Author)
Format: Book
Published: The Company of Biologists, 2015-08-01T00:00:00Z.
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