The role of Lyn kinase in the development of imatinib resistance in chronic myelogenous leukemia

Imatinib mesylate, a small-molecule inhibitor of BCRABL tyrosine kinase activity, has emerged as the well-recognized standard of treatment for chronic myelogenous leukemia (CML). Indeed, both its efficacy, tolerability, as well as cost-effectiveness have been clearly proven...

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Bibliographic Details
Main Authors: Camillo Porta (Author), Federica Tagliani (Author)
Format: Book
Published: Frontiers Media S.A., 2011-12-01T00:00:00Z.
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Summary:Imatinib mesylate, a small-molecule inhibitor of BCRABL tyrosine kinase activity, has emerged as the well-recognized standard of treatment for chronic myelogenous leukemia (CML). Indeed, both its efficacy, tolerability, as well as cost-effectiveness have been clearly proven...
Item Description:10.4081/oncol.2008.67
1970-5557
1970-5565