The role of Lyn kinase in the development of imatinib resistance in chronic myelogenous leukemia
Imatinib mesylate, a small-molecule inhibitor of BCRABL tyrosine kinase activity, has emerged as the well-recognized standard of treatment for chronic myelogenous leukemia (CML). Indeed, both its efficacy, tolerability, as well as cost-effectiveness have been clearly proven...
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Main Authors: | , |
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Format: | Book |
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Frontiers Media S.A.,
2011-12-01T00:00:00Z.
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Summary: | Imatinib mesylate, a small-molecule inhibitor of BCRABL tyrosine kinase activity, has emerged as the well-recognized standard of treatment for chronic myelogenous leukemia (CML). Indeed, both its efficacy, tolerability, as well as cost-effectiveness have been clearly proven... |
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Item Description: | 10.4081/oncol.2008.67 1970-5557 1970-5565 |