Best Practices to Maximize the Use and Reuse of Quantitative and Systems Pharmacology Models: Recommendations From the United Kingdom Quantitative and Systems Pharmacology Network

The lack of standardization in the way that quantitative and systems pharmacology (QSP) models are developed, tested, and documented hinders their reproducibility, reusability, and expansion or reduction to alternative contexts. This in turn undermines the potential impact of QSP in academic, indust...

Full description

Saved in:
Bibliographic Details
Main Authors: Lourdes Cucurull‐Sanchez (Author), Michael J. Chappell (Author), Vijayalakshmi Chelliah (Author), S. Y. Amy Cheung (Author), Gianne Derks (Author), Mark Penney (Author), Alex Phipps (Author), Rahuman S. Malik‐Sheriff (Author), Jon Timmis (Author), Marcus J. Tindall (Author), Piet H. van derGraaf (Author), Paolo Vicini (Author), James W. T. Yates (Author)
Format: Book
Published: Wiley, 2019-05-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The lack of standardization in the way that quantitative and systems pharmacology (QSP) models are developed, tested, and documented hinders their reproducibility, reusability, and expansion or reduction to alternative contexts. This in turn undermines the potential impact of QSP in academic, industrial, and regulatory frameworks. This article presents a minimum set of recommendations from the UK Quantitative and Systems Pharmacology Network (UK QSP Network) to guide QSP practitioners seeking to maximize their impact, and stakeholders considering the use of QSP models in their environment.
Item Description:2163-8306
10.1002/psp4.12381