Western blot using Trypanosoma cruzi chimeric recombinant proteins for the serodiagnosis of chronic Chagas disease: A proof-of-concept study.

• Main Authors: Ramona Tavares Daltro (Author), Emily Ferreira Santos (Author), Ângelo Antônio Oliveira Silva (Author), Natália Erdens Maron Freitas (Author), Leonardo Maia Leony (Author), Larissa Carvalho Medrado Vasconcelos (Author), Alejandro Ostermayer Luquetti (Author), Paola Alejandra Fiorani Celedon (Author), Nilson Ivo Tonin Zanchin (Author), Carlos Gustavo Regis-Silva (Author), Fred Luciano Neves Santos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Chagas disease (CD) is caused by Trypanosoma cruzi. The chronic phase of CD is characterized by the presence of IgG anti-T. cruzi antibodies; and diagnosis is performed by serological methods. Because there is no reliable test that can be used as a reference test, WHO...