Statistical optimization of dithranol-loaded solid lipid nanoparticles using factorial design

• প্রধান লেখক: Makarand Suresh Gambhire (লেখক), Mangesh Ramesh Bhalekar (লেখক), Vaishali Makarand Gambhire (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Universidade de São Paulo, 2011-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

This study describes a 3² full factorial experimental design to optimize the formulation of dithranol (DTH) loaded solid lipid nanoparticles (SLN) by the pre-emulsion ultrasonication method. The variables drug: lipid ratio and sonication time were studied at three levels and arranged in a 3² factori...