Statistical optimization of dithranol-loaded solid lipid nanoparticles using factorial design
This study describes a 3² full factorial experimental design to optimize the formulation of dithranol (DTH) loaded solid lipid nanoparticles (SLN) by the pre-emulsion ultrasonication method. The variables drug: lipid ratio and sonication time were studied at three levels and arranged in a 3² factori...
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Universidade de São Paulo,
2011-09-01T00:00:00Z.
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