Statistical optimization of dithranol-loaded solid lipid nanoparticles using factorial design

• 主要な著者: Makarand Suresh Gambhire (著者), Mangesh Ramesh Bhalekar (著者), Vaishali Makarand Gambhire (著者)
• フォーマット: 図書
• 出版事項: Universidade de São Paulo, 2011-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

This study describes a 3² full factorial experimental design to optimize the formulation of dithranol (DTH) loaded solid lipid nanoparticles (SLN) by the pre-emulsion ultrasonication method. The variables drug: lipid ratio and sonication time were studied at three levels and arranged in a 3² factori...