Statistical optimization of dithranol-loaded solid lipid nanoparticles using factorial design

• Những tác giả chính: Makarand Suresh Gambhire (Tác giả), Mangesh Ramesh Bhalekar (Tác giả), Vaishali Makarand Gambhire (Tác giả)
• Định dạng: Sách
• Được phát hành: Universidade de São Paulo, 2011-09-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

This study describes a 3² full factorial experimental design to optimize the formulation of dithranol (DTH) loaded solid lipid nanoparticles (SLN) by the pre-emulsion ultrasonication method. The variables drug: lipid ratio and sonication time were studied at three levels and arranged in a 3² factori...