Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma

• المؤلفون الرئيسيون: Norihiro Sato (مؤلف), Xiao-Bo Cheng (مؤلف), Shiro Kohi (مؤلف), Atsuhiro Koga (مؤلف), Keiji Hirata (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2016-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Progression of cancer is often associated with interactions between cancer cells and extracellular matrix (ECM) surrounding them. Increasing evidence has suggested that accumulation of hyaluronan (HA), a major component of ECM, provides a favorable microenvironment for cancer progression. Pancreatic...