Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma

• Main Authors: Norihiro Sato (Author), Xiao-Bo Cheng (Author), Shiro Kohi (Author), Atsuhiro Koga (Author), Keiji Hirata (Author)
• Format: Bog
• Udgivet: Elsevier, 2016-03-01T00:00:00Z.
• Fag: article
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Progression of cancer is often associated with interactions between cancer cells and extracellular matrix (ECM) surrounding them. Increasing evidence has suggested that accumulation of hyaluronan (HA), a major component of ECM, provides a favorable microenvironment for cancer progression. Pancreatic...