Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma

• Autori principali: Norihiro Sato (Autore), Xiao-Bo Cheng (Autore), Shiro Kohi (Autore), Atsuhiro Koga (Autore), Keiji Hirata (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2016-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Progression of cancer is often associated with interactions between cancer cells and extracellular matrix (ECM) surrounding them. Increasing evidence has suggested that accumulation of hyaluronan (HA), a major component of ECM, provides a favorable microenvironment for cancer progression. Pancreatic...